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  • Publication

    1. Minckley TF, Salvagio LA, Fudge DH, Verhey K, Markus SM, Qin Y. (2023) Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C. Journal of Cell Biology, 222(8), e202208121. Link
    2. Dischler AM, Maslar D, Zhang C, Qin Y. (2022) Development and characterization of a red fluorescent protein-based sensor RZnP1 for the detection of cytosolic Zn2+. ACS sensors 7(12):3838-3845. Link
    3. Zhang C, Dischler A, Glover K, Qin Y. (2022) Neuronal signaling of zinc: from detection and modulation to function. Open Biology, 12(9): 220188.Link
    4. Sandberg AA, Manning E, Wilkins HM, Mazzarino R, Minckley T, Swerdlow RH, Patterson D, Qin Y, Linseman DA. (2022) Mitochondrial Targeting of Amyloid-β Protein Precursor Intracellular Domain Induces Hippocampal Cell Death via a Mechanism Distinct from Amyloid-β. J Alzheimers Dis, 86(4):1727-1744. Link
    5. Gu M, Hu M, Minckley T, Pinchi P, Xu H, Qin Y, Du W.  (2022) A protocol to measure lysosomal Zn2+ release through a genetically encoded Zn2+ indicator. STAR protocols, 3(2), 101453.Link
    6. Ahmed J, Fitch TC, Donnelly CM, Joseph JJ, Bassil MM, Son A, Zhang C, Ledreux A, Horowitz S, Qin, Y, Paredes D, Kumar S. (2022) Foldamers reveal and validate novel therapeutic targets associated with toxic α-synuclein self-assembly. Nature Communications, 13(1): 2273. Link
    7. Zhang C, Maslar D, Minckley TF, LeJeune KD, Qin Y. (2021) Spontaneous, synchronous zinc spikes oscillate with neural excitability and calcium spikes in primary hippocampal neuron culture. J Neurochem, doi:10.1111/jnc.15334. Link
    8. Minckley TF, Zhang C, Fudge DH, Dischler AM, LeJeune KD, Xu, H, Qin Y. (2019) Sub-nanomolar sensitive GZnP3 reveals TRPML1-mediated neuronal Zn2+signals. Nature Communications, 10, article number: 4806. Link
    9. Fudge DH, Black R, Qin Y. (2018) Optical recording of cellular zinc dynamics with zinc-finger-based biosensors. Zinc Finger Proteins, 103-112. Link
    10. Fudge DH, Black R, Son L, LeJeune K, Qin Y. (2018) Optical recording of Zn2+ dynamics in the mitochondrial matrix and intermembrane space with the GZnP2 sensor. ACS Chemical Biology, 13 (7): 1897-1905. Link
    11. Qin Y, Gee KR, Jin Q, Lai B, Qian C, Colvin RA. (2017) Current methods used to probe and quantify intracellular total and free Zn (II) dynamics, and subcellular distribution in cultured neurons. Metals in the Brain: Measurement and Imaging, 195-224. Link
    12. Fiedler BL, Van Buskirk S, Carter KP, Qin Y, Carpenter MC, Palmer AE, Jimenez R. (2017) Droplet microfluidic flow cytometer for sorting on transient cellular responses of genetically-encoded sensors. Analytical chemistry 89(1), 711-719.Link
    13. Qin Y*, Sammond DW, Braselmann E., Carpenter MC, & Palmer AE*. (2016) Development of an optical Zn2+ probe based on a single fluorescent protein. ACS Chemical Biology, 11(10), 2744-2751. (*co-correspondence author) PMCID: PMC5081268. Link
    14. Qin Y, Miranda JG, Stoddard CI, Dean KM, Galati DF; Palmer AE. (2013) Direct comparison of a genetically encoded sensor and small molecule indicator: implications for quantification of cytosolic Zn2+. ACS Chemical Biology 8(11), 2366-2371. Link
    15. Miranda JG, Weaver AL, Qin Y, Park JG, Stoddard CI, et al. (2012) New Alternately Colored FRET Sensors for Simultaneous Monitoring of Zn2+ in Multiple Cellular Locations. PLOS ONE 7(11), e49371. Link
    16. Geng X, Huang C, Qin Y, McCombs J, Yuan Q, Harry BL, Palmer AE, Xia N, and Xue D. (2012). Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction. Proceedings of the National Academy of Sciences 109(45),18471-6. Link
    17. Park JG, Qin Y, Palmer AE. (2012). New sensors for quantitative measurement of mitochondrial Zn2+. ACS Chemical Biology 7(10),1636-40. Link
    18. Dean K, Qin Y, Palmer AE. (2012). Visualizing Metal Ions in Cells: An Overview of Analytical Techniques, Approaches, and Probes. Biochimica et Biophysica Acta 1823(9), 1406-15. Link
    19. West DC, Qin Y, Peterson QP, Thomas DL, Palchaudhuri R, Morrison KC, Lucas PW, Palmer AE, Fan TM, Hergenrother PJ. (2012). Differential Effects of Procaspase-3 Activating Compounds in the Induction of Cancer Cell Death. Molecular Pharmaceutics 9(5), 1425-34. Link
    20. Qin Y, Dittmer PJ, Park JG, Jansen KB, Palmer AE. (2011). Measuring steady-state and dynamic endoplasmic reticulum and Golgi Zn2+ with genetically encoded sensors. Proceedings of the National Academy of Sciences 108(18), 7351-6. Link
    21. Palmer AE, Qin Y, Park JG, McCombs JE. (2011). Design and application of genetically encoded biosensors. Trends in Biotechnology 29(3), 144-52. Link
    22. Qin Y, Thomas D, Fontaine CP, Colvin RA. (2009). Silencing of ZnT1 reduces Zn2+ efflux in Cultured Cortical Neurons. Neuroscience letters 450(2), 206-210. Link
    23. Qin Y, Thomas D, Fontaine CP, Colvin RA. (2008). Mechanisms of Zn2+ Efflux in Cultured Cortical Neurons. Journal of neurochemistry 107, 1304-1313. Link
    24. Qin Y, Gao J, Zhang TT, Zhao L, Wu HW, Xu L, Xu JY, Lu SY. (2002). Changes of thioredoxin mRNA level in neurons insulted by sodium azide, Shi Yan Sheng Wu Xue Bao 35(1), 26-30.

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This portfolio last updated: 30-Jun-2023 9:14 AM